I have just started to use Mozy for online backups, so far I`m impressed with the service. I also run a couple of local backup jobs every day (had a server disaster last February with an incomplete backup, I never want to live through that again!).
For remote access I use Windows Remote Desktop (Terminal Services) and a LINUX VPN (Virtual Private Network). Both were essentially free and with the proper router and firewall configuration they are also pretty secure. They allow me to control and connect to my business from anywhere - in the last two months I have run my Hawaii-based business from both Sydney Australia and Montreal Canada, can`t imagine being more remote than that!
A web site with a document portal would also be a good way to share files with your office staff.
Hope this helps, good luck.