I actually was in negotiations with QVC once for a patented invention of mine. They found me at an inventor`s expo. I think it`s pretty rare of them to take on the development of a product, but I can tell you first-hand it`s been done because that`s what they wanted to do with me. We ended up not agreeing on things and the deal fell through unfortunately. Looking back, I kind of wish I had taken the chance with them - but I also had 2 other companies I was negotiating with. I ended up signing with one of them instead. A few months later, that fell through as well. (Thank goodness I asked for some money up front!)
Nowadays, from what I understand, they want the product already in production and want to purchase at least $20k wholesale for the first order. You have to have the product to them in 3 months.
You can always mail them a sample and see what they say.